Plasma therapy dropped from Covid management guidelines

So far widely being used as most effective therapy to treat Covid patients in India, the government has removed convalescent plasma therapy from the country’s clinical management guidelines on Covid-19.

The move comes following suggestion of an expert group which found that the therapy was ineffective in reducing the progression to severe Covid disease or death.

Taking cognisance of the findings, Indian Council of Medical Research (ICMR) has revised the clinical guidance for management of adult Covid-19 patients and dropped plasma therapy.

The ICMR took the decision after it ensured that the plasma therapy is not much beneficial. It was based on examination of recovery trial documents and consideration of synthesis of global evidence which is not supporting the usage of plasma therapy.

The earlier guidelines allowed “off label” use of plasma therapy at the stage of early moderate disease, that is, within seven days of the onset of symptoms and if there is availability of a high titre donor plasma.

India had earlier conducted the world’s largest randomised controlled trials to study the efficacy of plasma therapy. The study, which came out in September last year, showed that plasma therapy failed to save people dying from Covid-19.

Recently, British medical journal, Lancet published strong evidence reconfirming that plasma is not effective in reducing deaths in Covid-19 hospitalisation.

The ICMR decision, announced on Monday, followed a meeting of the ICMR National Task Force for Covid-19 on Friday. In the meeting, all members voted in favour of doing away with convalescent plasma therapy for Covid-19 treatment citing its ineffectiveness and inappropriate use in several cases.

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Arushi Sana is the Co Founder of NYK Daily. She was a Forensic Data Analyst previously employed with EY (Ernst & Young). She aims to develop a global community of knowledge and journalism par excellence through this News Platform. Arushi holds a degree in Computer Science Engineering. She is also a Mentor for women suffering from Mental Health, and helps them in becoming published authors. Helping and educating people always came naturally to Arushi. She is a writer, political researcher, a social worker and a singer with a flair for languages. Travel and nature are the biggest spiritual getaways for her. She believes Yoga and communication can make the world a better place, and is optimistic of a bright yet mysterious future!

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